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Botulinum Toxin to Treat Hyperhidrosis and Spasticity



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The toxin injection can relieve spasticity symptoms, including hyperhidrosis and movement disorder. The toxin can have an effect on the muscles for three to five months. The toxin's duration depends on many factors including the size and spasticity of the affected muscle, as well as the type of treatment received.

Treatment of spasticity

Many studies have shown positive results from botulinum-toxin treatments for spasticity among patients with cerebral palsy. The effectiveness of the treatment depends on several variables, including muscle selection, aging, and therapy. Letibotulinum toxins A proved to be more effective than placebo in a phase III clinical trial. Secondary analyses were done to determine the effectiveness of letibotulinum toxin A. This was determined by changes in spasticity rating scales.

Botulinum toxin injections typically begin working within two weeks. Although the effects of one injection can last for up to six months however, they wear off after a few months. You may need to give several injections to maintain the effect. In order to maximize the effect of botulinum, some patients will need to have occupational therapy as well as physical therapy.


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Hyperhidrosis Treatment

Botulinumtoxin type A injections local to the area have been shown to be effective for treating primary hypohidrosis. These injections can be repeated for up to six months to see the desired effect. This treatment can be considered a viable option to treat hyperhidrosis axillary. It is reasonably affordable. This treatment is safer than other options and requires a shorter recovery period.


For primary focal hyperhidrosis, symptoms can be difficult to treat. Botulinumtoxin A is injected underneath the skin to inhibit the release and neurotransmission of acetylcholine. Botulinumtoxin A treatment has been effective in treating excessive sweating. It has also led to dramatic improvements in patients' quality of life.

Treatment for movement disorder

Botulinumtoxin for movement disorders has seen positive results in patients with focal dystonia, spinal myoclonus, and other types of movement disorders. The location of the affected muscle and its method of administration are key factors in determining the effectiveness of treatment. This article will discuss the effectiveness of the medication, its indications and the research that supports it.

Botulinumtoxin is used to treat various movement disorders. It can be used for cervical dystonia or generalized dystonia. Both are caused by overactive neck muscles and generalized dysfunction, which affects all muscle groups. The treatment can also be used for symptoms associated with young-onset Parkinson’s disease like motor fluctuations and dyskinesias. Other uses include the treatment for tremor, disorders such as drooling & constipation.


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Botulinum toxins are safe

Botulinum toxin type A (Botox) is a neurotoxin that inhibits acetylcholine production by inhibiting the docking of acetylcholine vesicles at the inner surface of a cellular membrane. This prevents Acetylcholine (which is responsible for muscle contraction) from reaching neuromuscular joints. The result of this toxicity is a decrease in muscle tone.

Similar results were achieved using the Vancouver scar (VMS) as well as the visual analogue scales (VAS). The MD of the width of the scar was -1.06 (99.5%CI, -1.10 to -0.02). In the other study, a single botulinum toxin treatment produced a 0-mm scarring, with no significant differences between treatments. While the new study's design looks promising, future research needs to examine different doses of botulinum toxin and the differences between pre-surgical and post-surgical injection periods.


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Botulinum Toxin to Treat Hyperhidrosis and Spasticity